ABSTRACT
Aim: To know organism most commonly found in bile, to study and compare the incidence of gall stone in culture negative versus culture positive bile. bile will be collected from removed gall bladder after the patientMethod: undergoes cholecystectomy and subjected to culture and sensitivity, and the result of the organism found will be tabulated and incidence of which organism is highest will be known in the study and which antibiotic was it most sensitive to will be noted. A total of 29 patients were included in the study. Out of 29 calculous cholelithiasisResults: patients only 10 of them had positive bile culture. More than 50 percent of patients had growth belonging to the Enterobacter family, and highest sensitivity was for imipenem antibiotic.